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Effectiveness of technology-based distance physical rehabilitation interventions on physical activity and walking in multiple sclerosis: a systematic review and meta-analysis of randomized controlled trials

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Effectiveness of technology-based distance physical rehabilitation interventions on physical activity and walking in multiple sclerosis: a systematic review and meta-analysis of randomized controlled trials

Effectiveness of technology-based distance physical rehabilitation interventions on physical activity and walking in multiple sclerosis: a systematic review and meta-analysis of randomized controlled trials

Objective: To determine the effectiveness of technology-based distance physical rehabilitation intervention in multiple sclerosis (MS) on physical activity and walking. Data sources: A systematic literature search was conducted in seven databases for January 2000–September 2016. Randomized controlled trials of technology-based distance physical rehabilitation interventions on physical activity and walking outcome measures were included. Methods: Study quality was determined by Furlan (2015) and a meta-analysis was performed. In addition, a subanalysis of technologies and an additional analysis comparing to no treatment were conducted. Results: The meta-analysis consisted of 11 studies. The methodological quality was good (8/13). The Internet, telephone, exergaming and pedometers were the technologies enabling distance physical rehabilitation. Technology-based distance physical rehabilitation had a large effect on physical activity (Standard mean difference (SMD) 0.59; 95% confidence interval (95% CI) 0.38 to 0.79; p<0.00001) compared to control group with usual care, minimal treatment, and no treatment. A large effect was also observed on physical activity (SMD 0.59; 95% CI 0.34 to 0.83; p<0.00001) when compared to no treatment alone. There were no differences in walking and the subanalysis of technologies. Conclusion: Technology-based distance physical rehabilitation increased physical activity among persons with MS, but further research on walking in MS is needed.

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