Despite numerous studies on evidence-based practice, knowledge of midwives and attitudes towards midwifery practice, many issues remain open, including evidence-based practice in obstetrics in the Republic of Kazakhstan. Therefore, it is necessary to study in depth the knowledge/skills, attitudes, and practice of midwifery based on evidence among midwives in the Republic of Kazakhstan. The aim of this research was to study midwives' knowledge/skills, practice, and attitudes towards evidence-based practice to get valuable information for the development of the quality of midwifery care in Kazakhstan. Quantitative cross-sectional research was used to describe the current state of evidence-based practice in Kazakhstan. The survey tool was the Evidence-Based Practice Questionnaire developed by Upton and Upton (2006) to assess Evidence-Based Practice knowledge, attitudes, and practices among midwives. In total, 304 practical midwives responded to the questionnaire between 2018 and 2019. The results show that the average level of evidence-based practice was 2.4, attitudes towards EBP 2.94, knowledge/skills in relation to evidence-based practice 2.74 and showed a very low result. Similarly low results were found in all groups for perceptions, attitudes, and knowledge in relation to evidence-based practice. All activities related to the practice of the evidence-based approach were rated as important. Understanding the concept and introducing evidence-based practice are necessary competencies in nursing education, not only for students, but also for teachers. More targeted research is needed related to the introduction of a scientifically based approach to nursing education, nursing practice and management in Kazakhstan.