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Pressure ulcers are known as the localized damage to the skin that usually occurs due to bony prominence or related to medical devices and over the years, there has been an increasingly alarming prevalence of pressure ulcers particularly among elderly patients, that tend to decrease their mobility and causes decline in quality of life and quality of nursing care provided. For nurses especially, the prevention and management of pressure ulcers is a top priority; however, amidst different interventions applied, certain difficulties and challenges are still experienced by nurses as part of pressure ulcer prevention. The research aimed at assessing the current experiences of nurses towards the prevention of pressure ulcers and understand its challenges and the purpose was to find appropriate interventions or measures in enhancing pressure ulcer prevention among elderly that can lead to positive changes in nurses’ attitudes, methodologies, and practices. The method utilized was the literature review analysis. A total of 14 articles were chosen from three different databases: CINAHL, PMC, and Google Scholar. The original data was sub jected to content analysis to present the nurses’ experiences, challenges, and interventions towards pres sure ulcer prevention. The main categories identified are skin management interventions, nursing management interventions, pain and disease management interventions, and nutrition-related interventions. The findings provided key information on what specific interventions or measures are being applied by nurses that can help ensure to better manage and treat pressure ulcers that will help improve the overall condition and quality of life of their patients, and at the same time, can also help them to improve their attitude and practices towards pressure ulcer prevention and management. It also provided key understanding on what barriers or challenges are hindering nurses in providing effective pressure ulcer prevention for their elderly patients. The research recognizes the limitations of the study, thus, recommending future research on the impacts of specific interventions used for pressure ulcer and on the adequacy and effectiveness of tools and guidelines provided for nurses for pressure ulcer prevention.