Purpose: Super-tall towers have surfaced as a pragmatic remedy to meet the escalating requisites for both residential and commercial areas and to stimulate economic growth in the Middle East. In this unique regional context, optimizing spatial usage stands as a paramount consideration in the architectural design of skyscrapers. Despite the proliferation of super-tall towers, there exists a conspicuous dearth of comprehensive research pertaining to space efficiency in Middle Eastern skyscrapers. This study endeavors to bridge this substantial gap in the literature. Design/methodology/approach: The research methodology utilized in this paper adopts a case study approach to accumulate data regarding super-tall towers in the Middle East, with a specific focus on investigating space efficiency. A total of 27 super-tall tower cases from the Middle East were encompassed within the analytical framework. Findings: Key findings can be succinctly summarized as follows: (1) average space efficiency was 75.5%, with values fluctuating between a minimum of 63% and a maximum of 84%; (2) average ratio of the core area to the gross floor area (GFA) registered 21.3%, encompassing a spectrum ranging from 11% to 36%; (3) predominantly, Middle Eastern skyscrapers exhibited a prismatic architectural form coupled with a central core typology. This architectural configuration mostly catered to residential and mixed-use functions; (4) the combination of concrete and outrigger frame systems was the most frequently utilized; (5) as the height of the tower increased, space efficiency tended to experience a gradual decline and (6) no significant discernible disparities were detected in the impact of diverse load-bearing systems and architectural forms on space efficiency. Originality/value: Despite the proliferation of super-tall towers, there exists a conspicuous dearth of comprehensive research pertaining to space efficiency in Middle Eastern skyscrapers. This study endeavors to bridge this substantial gap in the literature.